Manufacturer Oem Digital Accurate Voice Alarm System Medical Treatment Thalassemia Micro Syringe Pump

Clinical application

Observation and nursing care of intravenous injection of morphine precision injection pump in the treatment of advanced cancer pain

Cancer pain is a common symptom of patients with advanced malignant tumors, and it worsens with the progression of the disease, seriously affecting the quality of life of patients. Therefore, effective control of cancer pain has become an important demand in the treatment of patients with advanced malignant tumors. Morphine is a powerful opioid analgesic with good analgesic effect without capping effect and obvious organ function damage
It is widely used, but it also has certain toxic and side effects, and corresponding nursing measures should be taken when administering the drug.
1. Data and methods
1.1 General data Sixty-eight patients with advanced intractable cancer pain were enrolled, ranging in age from 42 to 69 years, with an average age of (56.3 ± 10.7) years. Types of disease: 26 cases of lung cancer, 24 cases of breast cancer and 8 cases of liver cancer. All patients had received antipyretic and analgesic drugs, tramadol and other treatments before, and had poor effects on the severe methContin resistant external patch Dorigil and repeated subcutaneous injection of morphine.
1.2 Analgesia Methods All patients were treated with morphine micro-injection pump for white control analgesia. The total capacity of the pump used is 100mL. The continuous injection of morphine was calculated according to the oral or intramuscical morphine dosage of the patient. Generally, the initial dose was (46.50-4-1767)mg·d ~, and the treatment end dose was (360.60 ± 120.40)mg·d ~. Normal saline was added to make the total volume reach the total pump capacity of 100mL. Then the infusion was pumped into the body at the rate of 2mL·h, 0.5 mL each time, and the dosage could last for about 48h. When the analgesic effect was not good, the patient could add morphine by self-control. The degree of pain was re-evaluated after 24 hours of use, and the dosage and method of administration were adjusted according to the degree of pain until satisfactory analgesic effect was achieved.
1.3 The evaluation of morphine related side effects is mainly based on the following aspects: gastrointestinal symptoms, including nausea, vomiting and constipation; Symptoms of autonomic nervous system, urinary retention, dry mouth, and positional hypotension; Central nervous system symptoms, drowsiness, hallucinations, delirium, impaired recognition, respiratory depression, muscle spasms, hyperalgesia, etc. Skin symptoms, excessive sweating, itching, rash, etc.
2 Results
2.1 Analgesic effect Among 68 patients, 66 (97.1%) had satisfactory analgesic effect, and the VAS score was controlled below 3 points. 5 of them underwent abdominal plexus block to reduce the dose of morphine. The analgesic effect was poor in the remaining 2 patients, and the pain was relieved after continuous epidural analgesia and intraspinal damage block.
2.2 Side effects Side effects included constipation in 48 cases (70. There were 524 patients with itching (35.3%), 3 patients with vomiting (4.4%), 2 patients with sleepiness (2.9%), 6 patients with dyuria (8.8%), and 3 patients with dermatomitchy (4.4%), all of which were treated well.
Respiratory depression is a serious toxic side effect of morphine, which may be related to the fact that morphine can reduce the sensitivity of the respiratory center of the medulla bulbar to carbon dioxide, inhibit the respiratory regulatory center of the pontine, and further slow down the respiratory frequency and inhibit respiration. Respiratory depression occurred frequently when morphine was administered intravenously for 5-10min and after subcutaneous or intramuscular injection of 30-9omin. Although the incidence of respiratory depression is extremely low, due to its severity, nurses should pay close attention to the changes in the patient’s vital signs. If there is difficult awakening, constriction of the pupil, and significant reduction in the number of breaths, they should inform the doctor, pay attention to the possibility of respiratory depression, and conduct corresponding treatment. Patients with severe symptoms may consider suspending the pump
3. Summary
When morphine is injected intravenously for the treatment of advanced persistent cancer pain, the nursing staff should actively explain the relevant knowledge of cancer pain treatment to the patient, and inform the patient of the drug properties, medication methods, precautions, toxic and side effects of morphine, especially to correct the patient’s fear of morphine addiction. During the treatment period, the changes of the condition and vital signs were closely observed, and the toxicity of morphine was detected and treated in time
Side effects, which are conducive to the smooth progress of the pump analgesia. In conclusion, the effect of morphine microinjection pump intravenous pump in the treatment of advanced intractable cancer pain is satisfactory, and it is simple and easy to improve the quality of life of such patients.